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Furthermore, there are interactions between the hypothalamic-pituitary-ovarian axis and many neurotransmitters For example, disruptions of the hypothalamic-pituitary-ovarian axis can result in reduced Mel secretion at night [34], and also effect 5-HT [257] and DA [258]

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Several studies have identified ACSL4 and LPCAT3 as key determinants of susceptibility to ferroptosis, especially ACS4, which is considered a biomarker of ferroptosis (42)